منابع مشابه
TEACHERS’ TOPICS Insulin and Oral Antidiabetic Agents
The current manuscript describes an overview for therapeutic approaches to treat diabetes mellitus. Detailed presentation of the role of insulin in both disease state development and therapy is given. The article also addresses the classification, chemistry, pharmacokinetic properties, dosage forms, mechanisms of action, and therapeutic indications of oral anti-diabetic agents currently availab...
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India has the largest population of patients with type 2 diabetes mellitus. The conventional agents used to treat type 2 diabetes frequently exhibit reduced efficacy over time leading to inadequate glycaemic control and are also associated with adverse effects. Hence, there is a need for alternative therapies that can overcome the limitations associated with conventional antidiabetic agents. Th...
متن کاملSafe Oral Antidiabetic Agents in Cardiac Patients: An Update
Cardiovascular disease is the major cause of mortality among patients with type 2 diabetes mellitus, accounting for 60-80% of death in these patients. Despite recent studies demonstrating likely benefit of good glycaemic control in decreasing cardiovascular risk in type 2 DM, there have been lingering concerns about potential adverse cardiovascular effects of insulin secretagogues, specifically...
متن کاملThe Effect of Oral Antidiabetic Agents on A1C Levels
OBJECTIVE Previous reviews of the effect of oral antidiabetic (OAD) agents on A1C levels summarized studies with varying designs and methodological approaches. Using predetermined methodological criteria, we evaluated the effect of OAD agents on A1C levels. RESEARCH DESIGN AND METHODS The Excerpta Medica (EMBASE), the Medical Literature Analysis and Retrieval System Online (MEDLINE), and the ...
متن کاملCardiovascular Safety of Oral Antidiabetic Agents: The Insulin Secretagogues
The prevalence of type 2 diabetes mellitus (T2DM) has increased rapidly over the past decade. In the Untied States, this increase has been greater than 40%. Obesity, which is closely linked to risk of developing T2DM, has likewise increased in prevalence by more than 60% during the same time period. Cardiovascular disease is the major cause of mortality among patients with T2DM, accounting for ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1959
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.5135.1474